The early antibiotic therapy in septic patients - milestone or sticking point?

Sepsis is one of the oldest and most elusive syndromes in medicine. Every effort should be made to treat these patients with the best available evidence. As a milestone, empiric antimicrobial therapy is essential in order to reduce morbidity and mortality of septic patients. As a sticking point, the...

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Autores principales: Bernhard, Michael, Lichtenstern, Christoph, Eckmann, Christian, Weigand, Markus A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331420/
https://www.ncbi.nlm.nih.gov/pubmed/25672873
http://dx.doi.org/10.1186/s13054-014-0671-1
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author Bernhard, Michael
Lichtenstern, Christoph
Eckmann, Christian
Weigand, Markus A
author_facet Bernhard, Michael
Lichtenstern, Christoph
Eckmann, Christian
Weigand, Markus A
author_sort Bernhard, Michael
collection PubMed
description Sepsis is one of the oldest and most elusive syndromes in medicine. Every effort should be made to treat these patients with the best available evidence. As a milestone, empiric antimicrobial therapy is essential in order to reduce morbidity and mortality of septic patients. As a sticking point, the use of broad-spectrum antimicrobial agents may be associated with induction of resistance among common pathogens.
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spelling pubmed-43314202015-02-19 The early antibiotic therapy in septic patients - milestone or sticking point? Bernhard, Michael Lichtenstern, Christoph Eckmann, Christian Weigand, Markus A Crit Care Commentary Sepsis is one of the oldest and most elusive syndromes in medicine. Every effort should be made to treat these patients with the best available evidence. As a milestone, empiric antimicrobial therapy is essential in order to reduce morbidity and mortality of septic patients. As a sticking point, the use of broad-spectrum antimicrobial agents may be associated with induction of resistance among common pathogens. BioMed Central 2014-11-30 2014 /pmc/articles/PMC4331420/ /pubmed/25672873 http://dx.doi.org/10.1186/s13054-014-0671-1 Text en © Bernhard et al.; licensee BioMed Central Ltd. 2014 The licensee has exclusive rights to distribute this article, in any medium, for 12 months following its publication. After this time, the article is available under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Commentary
Bernhard, Michael
Lichtenstern, Christoph
Eckmann, Christian
Weigand, Markus A
The early antibiotic therapy in septic patients - milestone or sticking point?
title The early antibiotic therapy in septic patients - milestone or sticking point?
title_full The early antibiotic therapy in septic patients - milestone or sticking point?
title_fullStr The early antibiotic therapy in septic patients - milestone or sticking point?
title_full_unstemmed The early antibiotic therapy in septic patients - milestone or sticking point?
title_short The early antibiotic therapy in septic patients - milestone or sticking point?
title_sort early antibiotic therapy in septic patients - milestone or sticking point?
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331420/
https://www.ncbi.nlm.nih.gov/pubmed/25672873
http://dx.doi.org/10.1186/s13054-014-0671-1
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