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Cleavage of Host Cytokeratin-6 by Lysine-Specific Gingipain Induces Gingival Inflammation in Periodontitis Patients

BACKGROUND/PURPOSE: Lysine-specific gingipain (Kgp) is a virulence factor secreted from Porphyromonas gingivalis (P. gingivalis), a major etiological bacterium of periodontal disease. Keratin intermediate filaments maintain the structural integrity of gingival epithelial cells, but are targeted by K...

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Detalles Bibliográficos
Autores principales:	Tancharoen, Salunya, Matsuyama, Takashi, Kawahara, Ko-ichi, Tanaka, Kenji, Lee, Lyang-Ja, Machigashira, Miho, Noguchi, Kazuyuki, Ito, Takashi, Imamura, Takahisa, Potempa, Jan, Kikuchi, Kiyoshi, Maruyama, Ikuro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331500/ https://www.ncbi.nlm.nih.gov/pubmed/25688865 http://dx.doi.org/10.1371/journal.pone.0117775

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