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Identification of Aortic Arch-Specific Quantitative Trait Loci for Atherosclerosis by an Intercross of DBA/2J and 129S6 Apolipoprotein E-Deficient Mice

The genetic background of apolipoprotein E (apoE) deficient mice influences atherosclerotic plaque development. We previously reported three quantitative trait loci (QTL), Aath1–Aath3, that affect aortic arch atherosclerosis independently of those in the aortic root in a cross between C57BL6 apoEKO...

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Detalles Bibliográficos
Autores principales: Kayashima, Yukako, Makhanova, Natalia A., Matsuki, Kota, Tomita, Hirofumi, Bennett, Brian J., Maeda, Nobuyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331513/
https://www.ncbi.nlm.nih.gov/pubmed/25689165
http://dx.doi.org/10.1371/journal.pone.0117478

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