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Identification of Modulators of the Nuclear Receptor Peroxisome Proliferator-Activated Receptor α (PPARα) in a Mouse Liver Gene Expression Compendium
The nuclear receptor family member peroxisome proliferator-activated receptor α (PPARα) is activated by therapeutic hypolipidemic drugs and environmentally-relevant chemicals to regulate genes involved in lipid transport and catabolism. Chronic activation of PPARα in rodents increases liver cancer i...
Autores principales: | Oshida, Keiyu, Vasani, Naresh, Thomas, Russell S., Applegate, Dawn, Rosen, Mitch, Abbott, Barbara, Lau, Christopher, Guo, Grace, Aleksunes, Lauren M., Klaassen, Curtis, Corton, J. Christopher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331523/ https://www.ncbi.nlm.nih.gov/pubmed/25689681 http://dx.doi.org/10.1371/journal.pone.0112655 |
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