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The HIV-1 Gp120/CXCR4 Axis Promotes CCR7 Ligand-Dependent CD4 T Cell Migration: CCR7 Homo- and CCR7/CXCR4 Hetero-Oligomer Formation as a Possible Mechanism for Up-Regulation of Functional CCR7

During human immunodeficiency virus (HIV) infection, enhanced migration of infected cells to lymph nodes leads to efficient propagation of HIV-1. The selective chemokine receptors, including CXCR4 and CCR7, may play a role in this process, yet the viral factors regulating chemokine-dependent T cell...

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Detalles Bibliográficos
Autores principales: Hayasaka, Haruko, Kobayashi, Daichi, Yoshimura, Hiromi, Nakayama, Emi E., Shioda, Tatsuo, Miyasaka, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331524/
https://www.ncbi.nlm.nih.gov/pubmed/25688986
http://dx.doi.org/10.1371/journal.pone.0117454