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Value of DSA in the Diagnostic Workup of Pulsatile Tinnitus

OBJECTIVES: Pulsatile tinnitus (PT) is a rare complaint, but can be a symptom of life-threatening disease. It is often caused by vascular pathologies, e.g. dural arteriovenous fistula (dAVF), arteriovenous malformation (AVM) or vascularized tumors. The current diagnostic pathway includes clinical ex...

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Autores principales: Deuschl, Cornelius, Göricke, Sophia, Gramsch, Carolin, Özkan, Neriman, Lehnerdt, Götz, Kastrup, Oliver, Ringelstein, Adrian, Wanke, Isabel, Forsting, Michael, Schlamann, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331557/
https://www.ncbi.nlm.nih.gov/pubmed/25689158
http://dx.doi.org/10.1371/journal.pone.0117814
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author Deuschl, Cornelius
Göricke, Sophia
Gramsch, Carolin
Özkan, Neriman
Lehnerdt, Götz
Kastrup, Oliver
Ringelstein, Adrian
Wanke, Isabel
Forsting, Michael
Schlamann, Marc
author_facet Deuschl, Cornelius
Göricke, Sophia
Gramsch, Carolin
Özkan, Neriman
Lehnerdt, Götz
Kastrup, Oliver
Ringelstein, Adrian
Wanke, Isabel
Forsting, Michael
Schlamann, Marc
author_sort Deuschl, Cornelius
collection PubMed
description OBJECTIVES: Pulsatile tinnitus (PT) is a rare complaint, but can be a symptom of life-threatening disease. It is often caused by vascular pathologies, e.g. dural arteriovenous fistula (dAVF), arteriovenous malformation (AVM) or vascularized tumors. The current diagnostic pathway includes clinical examination, cranial MRI and additional DSA. The aim of this study was to evaluate the diagnostic impact of DSA in the diagnostic workup of patients with PT in comparison to MRI alone. METHODS: Retrospectively, 54 consecutive patients with pulsatile tinnitus were evaluated. All patients had a diagnostic workup including cranial MRI and DSA. MRI examinations were blinded to the results of DSA and retrospectively analyzed in consensus by two experienced neuroradiologists. The MR-examinations were evaluated for each performed sequence separately: time-of-flight-angiography, ce-MRA, T2, ce-T1-sequence and ce-T1-sequence with fat saturation. RESULTS: 37 of the 54 patients revealed a pathology explaining PT on MRI, which was detected by the readers in 100% and proofed by means of DSA. 24 dAVF, four paraganglioma, two AVM and seven more pathologies were described. All patients without pathology on MRI did also not show any pathology in DSA. CONCLUSIONS: MR imaging is sufficient to exclude pathology in patients with pulsatile tinnitus.
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spelling pubmed-43315572015-02-24 Value of DSA in the Diagnostic Workup of Pulsatile Tinnitus Deuschl, Cornelius Göricke, Sophia Gramsch, Carolin Özkan, Neriman Lehnerdt, Götz Kastrup, Oliver Ringelstein, Adrian Wanke, Isabel Forsting, Michael Schlamann, Marc PLoS One Research Article OBJECTIVES: Pulsatile tinnitus (PT) is a rare complaint, but can be a symptom of life-threatening disease. It is often caused by vascular pathologies, e.g. dural arteriovenous fistula (dAVF), arteriovenous malformation (AVM) or vascularized tumors. The current diagnostic pathway includes clinical examination, cranial MRI and additional DSA. The aim of this study was to evaluate the diagnostic impact of DSA in the diagnostic workup of patients with PT in comparison to MRI alone. METHODS: Retrospectively, 54 consecutive patients with pulsatile tinnitus were evaluated. All patients had a diagnostic workup including cranial MRI and DSA. MRI examinations were blinded to the results of DSA and retrospectively analyzed in consensus by two experienced neuroradiologists. The MR-examinations were evaluated for each performed sequence separately: time-of-flight-angiography, ce-MRA, T2, ce-T1-sequence and ce-T1-sequence with fat saturation. RESULTS: 37 of the 54 patients revealed a pathology explaining PT on MRI, which was detected by the readers in 100% and proofed by means of DSA. 24 dAVF, four paraganglioma, two AVM and seven more pathologies were described. All patients without pathology on MRI did also not show any pathology in DSA. CONCLUSIONS: MR imaging is sufficient to exclude pathology in patients with pulsatile tinnitus. Public Library of Science 2015-02-17 /pmc/articles/PMC4331557/ /pubmed/25689158 http://dx.doi.org/10.1371/journal.pone.0117814 Text en © 2015 Deuschl et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Deuschl, Cornelius
Göricke, Sophia
Gramsch, Carolin
Özkan, Neriman
Lehnerdt, Götz
Kastrup, Oliver
Ringelstein, Adrian
Wanke, Isabel
Forsting, Michael
Schlamann, Marc
Value of DSA in the Diagnostic Workup of Pulsatile Tinnitus
title Value of DSA in the Diagnostic Workup of Pulsatile Tinnitus
title_full Value of DSA in the Diagnostic Workup of Pulsatile Tinnitus
title_fullStr Value of DSA in the Diagnostic Workup of Pulsatile Tinnitus
title_full_unstemmed Value of DSA in the Diagnostic Workup of Pulsatile Tinnitus
title_short Value of DSA in the Diagnostic Workup of Pulsatile Tinnitus
title_sort value of dsa in the diagnostic workup of pulsatile tinnitus
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331557/
https://www.ncbi.nlm.nih.gov/pubmed/25689158
http://dx.doi.org/10.1371/journal.pone.0117814
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