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The PPARα agonist fenofibrate suppresses B-cell lymphoma in mice by modulating lipid metabolism()()
Obesity is associated with an increased risk for malignant lymphoma development. We used Bcr/Abl transformed B cells to determine the impact of aggressive lymphoma formation on systemic lipid mobilization and turnover. In wild-type mice, tumor size significantly correlated with depletion of white ad...
Autores principales: | Huang, Jianfeng, Das, Suman Kumar, Jha, Pooja, Al Zoughbi, Wael, Schauer, Silvia, Claudel, Thierry, Sexl, Veronika, Vesely, Paul, Birner-Gruenberger, Ruth, Kratky, Dagmar, Trauner, Michael, Hoefler, Gerald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Pub. Co
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331670/ https://www.ncbi.nlm.nih.gov/pubmed/23628473 http://dx.doi.org/10.1016/j.bbalip.2013.04.012 |
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