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PIM-1 modulates cellular senescence and links IL-6 signaling to heterochromatin formation
Cellular senescence is a stable state of proliferative arrest that provides a barrier against malignant transformation and contributes to the antitumor activity of certain chemotherapies. Unexpectedly, we found that the expression of proto-oncogene PIM-1, which can promote tumorigenesis, is induced...
Autores principales: | Jin, Bo, Wang, Yu, Wu, Chen Lin, Liu, Kai Yu, Chen, Hao, Mao, Ze Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331745/ https://www.ncbi.nlm.nih.gov/pubmed/25040935 http://dx.doi.org/10.1111/acel.12249 |
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