Long-Term High-dose Oral Morphine in Phantom Limb Pain with No Addiction Risk

Chronic phantom limb pain (PLP) is a type of neuropathic pain, which is located in the missing/amputated limb. Phantom pain is difficult to treat as the exact basis of pain mechanism is still unknown. Various methods of treatment for PLP have been described, including pharmacological (NSAIDs, opioid...

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Detalles Bibliográficos
Autores principales: Kumar, Vinod, Garg, Rakesh, Bharati, Sachidanand Jee, Gupta, Nishkarsh, Bhatanagar, Sushma, Mishra, Seema, Balhara, Yatan Pal Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332137/
https://www.ncbi.nlm.nih.gov/pubmed/25709194
http://dx.doi.org/10.4103/0973-1075.150198
Descripción
Sumario:Chronic phantom limb pain (PLP) is a type of neuropathic pain, which is located in the missing/amputated limb. Phantom pain is difficult to treat as the exact basis of pain mechanism is still unknown. Various methods of treatment for PLP have been described, including pharmacological (NSAIDs, opioids, antiepileptic, antidepressants) and non-pharmacological (TENS, sympathectomy, deep brain stimulation and motor cortex stimulation). Opioids are used for the treatment of neuropathic pain and dose of opioid is determined based on its effect and thus there is no defined ceiling dose for opioids. We report a case where a patient receiving high-dose oral morphine for chronic cancer pain did not demonstrate signs of addiction.

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