Changing partners: transcription factors form different complexes on and off chromatin

The current knowledge on how protein–protein interactions regulate the function of transcription factors (TFs) has remained limited due to an incomplete knowledge of their interaction partners. In their recent work, Chen and colleagues (Li et al, 2015) analyse the interactome of 56 TFs and reveal di...

Descripción completa

Detalles Bibliográficos
Autores principales: Ji, Zongling, Sharrocks, Andrew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
News and Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332156/
https://www.ncbi.nlm.nih.gov/pubmed/25609651
http://dx.doi.org/10.15252/msb.20145936
_version_ 1782357856733888512
author Ji, Zongling
Sharrocks, Andrew D
author_facet Ji, Zongling
Sharrocks, Andrew D
author_sort Ji, Zongling
collection PubMed
description The current knowledge on how protein–protein interactions regulate the function of transcription factors (TFs) has remained limited due to an incomplete knowledge of their interaction partners. In their recent work, Chen and colleagues (Li et al, 2015) analyse the interactome of 56 TFs and reveal distinct chromatin-associated and soluble TF complexes.
format Online
Article
Text
id pubmed-4332156
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher BlackWell Publishing Ltd
record_format MEDLINE/PubMed
spelling pubmed-43321562015-03-09 Changing partners: transcription factors form different complexes on and off chromatin Ji, Zongling Sharrocks, Andrew D Mol Syst Biol News and Views The current knowledge on how protein–protein interactions regulate the function of transcription factors (TFs) has remained limited due to an incomplete knowledge of their interaction partners. In their recent work, Chen and colleagues (Li et al, 2015) analyse the interactome of 56 TFs and reveal distinct chromatin-associated and soluble TF complexes. BlackWell Publishing Ltd 2015-01-21 /pmc/articles/PMC4332156/ /pubmed/25609651 http://dx.doi.org/10.15252/msb.20145936 Text en © 2015 The Authors. Published under the terms of the CC BY 4.0 license http://creativecommons.org/licenses/by/4.0/ This is an open access article under the terms of the Creative Commons Attribution 4.0 License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle News and Views
Ji, Zongling
Sharrocks, Andrew D
Changing partners: transcription factors form different complexes on and off chromatin
title Changing partners: transcription factors form different complexes on and off chromatin
title_full Changing partners: transcription factors form different complexes on and off chromatin
title_fullStr Changing partners: transcription factors form different complexes on and off chromatin
title_full_unstemmed Changing partners: transcription factors form different complexes on and off chromatin
title_short Changing partners: transcription factors form different complexes on and off chromatin
title_sort changing partners: transcription factors form different complexes on and off chromatin
topic News and Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332156/
https://www.ncbi.nlm.nih.gov/pubmed/25609651
http://dx.doi.org/10.15252/msb.20145936
work_keys_str_mv AT jizongling changingpartnerstranscriptionfactorsformdifferentcomplexesonandoffchromatin
AT sharrocksandrewd changingpartnerstranscriptionfactorsformdifferentcomplexesonandoffchromatin

Ejemplares similares