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Collagen recognition and transmembrane signalling by discoidin domain receptors()

The discoidin domain receptors, DDR1 and DDR2, are two closely related receptor tyrosine kinases that are activated by triple-helical collagen in a slow and sustained manner. The DDRs have important roles in embryo development and their dysregulation is associated with human diseases, such as fibros...

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Detalles Bibliográficos
Autores principales: Carafoli, Federico, Hohenester, Erhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332414/
https://www.ncbi.nlm.nih.gov/pubmed/23128141
http://dx.doi.org/10.1016/j.bbapap.2012.10.014