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Hepatocyte-Specific Ablation of PP2A Catalytic Subunit α Attenuates Liver Fibrosis Progression via TGF-β1/Smad Signaling

Protein phosphatase 2A (PP2A), a family of the major serine/threonine phosphatases in cells, regulates many aspects of physiological processes. However, isoform-specific substrates and the biological role of each specific member of the PP2A family remain largely unknown. In this study, we investigat...

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Detalles Bibliográficos
Autores principales: Lu, Na, Liu, Yun, Tang, An, Chen, Lulu, Miao, Dengshun, Yuan, Xiaoqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332469/
https://www.ncbi.nlm.nih.gov/pubmed/25710025
http://dx.doi.org/10.1155/2015/794862

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