LSD1 Overexpression Is Associated with Poor Prognosis in Basal-Like Breast Cancer, and Sensitivity to PARP Inhibition

LSD1, a lysine-specific histone demethylase, is overexpressed in several types of cancers and linked to poor outcomes. In breast cancer, the significance of LSD1 overexpression is not clear. We have performed an in silico analysis to assess the relationship of LSD1 expression to clinical outcome. We...

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Detalles Bibliográficos
Autores principales: Nagasawa, Satoi, Sedukhina, Anna S., Nakagawa, Yuko, Maeda, Ichiro, Kubota, Manabu, Ohnuma, Shigeko, Tsugawa, Koichiro, Ohta, Tomohiko, Roche-Molina, Marta, Bernal, Juan A., Narváez, Ana J., Jeyasekharan, Anand D., Sato, Ko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332491/
https://www.ncbi.nlm.nih.gov/pubmed/25679396
http://dx.doi.org/10.1371/journal.pone.0118002

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