Analysis of Structural Flexibility of Damaged DNA Using Thiol-Tethered Oligonucleotide Duplexes

Bent structures are formed in DNA by the binding of small molecules or proteins. We developed a chemical method to detect bent DNA structures. Oligonucleotide duplexes in which two mercaptoalkyl groups were attached to the positions facing each other across the major groove were prepared. When the d...

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Detalles Bibliográficos
Autores principales: Fujita, Masashi, Watanabe, Shun, Yoshizawa, Mariko, Yamamoto, Junpei, Iwai, Shigenori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332495/
https://www.ncbi.nlm.nih.gov/pubmed/25679955
http://dx.doi.org/10.1371/journal.pone.0117798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332495/
https://www.ncbi.nlm.nih.gov/pubmed/25679955
http://dx.doi.org/10.1371/journal.pone.0117798

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