Sorafenib Ameliorates Renal Fibrosis through Inhibition of TGF-β-Induced Epithelial-Mesenchymal Transition

OBJECTIVE: This study was to investigate whether sorafenib can inhibit the progression of renal fibrosis and to study the possible mechanisms of this effect. METHODS: Eight-week-old rats were subjected to unilateral ureteral obstruction (UUO) and were intragastrically administered sorafenib, while c...

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Detalles Bibliográficos
Autores principales: Jia, Lining, Ma, Xiaotao, Gui, Baosong, Ge, Heng, Wang, Li, Ou, Yan, Tian, Lifang, Chen, Zhao, Duan, Zhaoyang, Han, Jin, Fu, Rongguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332653/
https://www.ncbi.nlm.nih.gov/pubmed/25679376
http://dx.doi.org/10.1371/journal.pone.0117757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332653/
https://www.ncbi.nlm.nih.gov/pubmed/25679376
http://dx.doi.org/10.1371/journal.pone.0117757

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