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Antigen Targeting to Dendritic Cells Allows the Identification of a CD4 T-Cell Epitope within an Immunodominant Trypanosoma cruzi Antigen

Targeting antigens to dendritic cells (DCs) by using hybrid monoclonal antibodies (mAbs) directed against DC receptors is known to improve activation and support long-lasting T cell responses. In the present work, we used the mAb αDEC205 fused to the Trypanosoma cruzi amastigote surface protein 2 (A...

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Detalles Bibliográficos
Autores principales:	Rampazo, Eline V., Amorim, Kelly N. S., Yamamoto, Marcio M., Panatieri, Raquel Hoffmann, Rodrigues, Mauricio M., Boscardin, Silvia B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332658/ https://www.ncbi.nlm.nih.gov/pubmed/25679777 http://dx.doi.org/10.1371/journal.pone.0117778

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