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Prenatal Stress Down-Regulates Reelin Expression by Methylation of Its Promoter and Induces Adult Behavioral Impairments in Rats
Prenatal stress causes predisposition to cognitive and emotional disturbances and is a risk factor towards the development of neuropsychiatric conditions like depression, bipolar disorders and schizophrenia. The extracellular protein Reelin, expressed by Cajal-Retzius cells during cortical developme...
Autores principales: | Palacios-García, Ismael, Lara-Vásquez, Ariel, Montiel, Juan F., Díaz-Véliz, Gabriela F., Sepúlveda, Hugo, Utreras, Elías, Montecino, Martín, González-Billault, Christian, Aboitiz, Francisco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332679/ https://www.ncbi.nlm.nih.gov/pubmed/25679528 http://dx.doi.org/10.1371/journal.pone.0117680 |
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