Cargando…
The mitochondrial dicarboxylate and 2-oxoglutarate carriers do not transport glutathione
Glutathione carries out vital protective roles within mitochondria, but is synthesised in the cytosol. Previous studies have suggested that the mitochondrial dicarboxylate and 2-oxoglutarate carriers were responsible for glutathione uptake. We set out to characterise the putative glutathione transpo...
Autores principales: | Booty, Lee M., King, Martin S., Thangaratnarajah, Chancievan, Majd, Homa, James, Andrew M., Kunji, Edmund R.S., Murphy, Michael P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science B.V
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332691/ https://www.ncbi.nlm.nih.gov/pubmed/25637873 http://dx.doi.org/10.1016/j.febslet.2015.01.027 |
Ejemplares similares
-
The SLC25 Carrier Family: Important Transport Proteins in Mitochondrial Physiology and Pathology
por: Kunji, Edmund R.S., et al.
Publicado: (2020) -
Pathogenic variants of the mitochondrial aspartate/glutamate carrier causing citrin deficiency
por: Tavoulari, Sotiria, et al.
Publicado: (2022) -
Calcium-induced conformational changes of the regulatory domain of human mitochondrial aspartate/glutamate carriers
por: Thangaratnarajah, Chancievan, et al.
Publicado: (2014) -
The yeast mitochondrial pyruvate carrier is a hetero‐dimer in its functional state
por: Tavoulari, Sotiria, et al.
Publicado: (2019) -
Key features of inhibitor binding to the human mitochondrial pyruvate carrier hetero-dimer
por: Tavoulari, Sotiria, et al.
Publicado: (2022)