Transcription of the var genes from a freshly-obtained field isolate of Plasmodium falciparum shows more variable switching patterns than long laboratory-adapted isolates

BACKGROUND: Antigenic variation in Plasmodium falciparum involves switching among multicopy var gene family and is responsible for immune evasion and the maintenance of chronic infections. Current understanding of var gene expression and switching patterns comes from experiments conducted on long la...

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Detalles Bibliográficos
Autores principales: Ye, Run, Zhang, Dongmei, Chen, Biaobang, Zhu, Yongqiang, Zhang, Yilong, Wang, Shengyue, Pan, Weiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332720/
https://www.ncbi.nlm.nih.gov/pubmed/25889871
http://dx.doi.org/10.1186/s12936-015-0565-y

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