The Transfection of BDNF to Dopamine Neurons Potentiates the Effect of Dopamine D3 Receptor Agonist Recovering the Striatal Innervation, Dendritic Spines and Motor Behavior in an Aged Rat Model of Parkinson’s Disease

The progressive degeneration of the dopamine neurons of the pars compacta of substantia nigra and the consequent loss of the dopamine innervation of the striatum leads to the impairment of motor behavior in Parkinson’s disease. Accordingly, an efficient therapy of the disease should protect and rege...

Descripción completa

Detalles Bibliográficos
Autores principales: Razgado-Hernandez, Luis F., Espadas-Alvarez, Armando J., Reyna-Velazquez, Patricia, Sierra-Sanchez, Arturo, Anaya-Martinez, Veronica, Jimenez-Estrada, Ismael, Bannon, Michael J., Martinez-Fong, Daniel, Aceves-Ruiz, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332861/
https://www.ncbi.nlm.nih.gov/pubmed/25693197
http://dx.doi.org/10.1371/journal.pone.0117391

Ejemplares similares

Ejemplares similares