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High Mobility Group Box 1 Induced Human Lung Myofibroblasts Differentiation and Enhanced Migration by Activation of MMP-9

High mobility group box 1 (HMGB1) is a nuclear protein that involves the binding with DNA and influences chromatin regulation and transcription. HMGB1 is also a cytokine that can activate monocytes and neutrophils involved in inflammation. In this study, we investigated the role of HMGB1 on cellular...

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Detalles Bibliográficos
Autores principales: Lee, Chen-Chen, Wang, Chien-Neng, Lee, Yueh-Lun, Tsai, Yi-Ru, Liu, Jau-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332862/
https://www.ncbi.nlm.nih.gov/pubmed/25692286
http://dx.doi.org/10.1371/journal.pone.0116393