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High Mobility Group Box 1 Induced Human Lung Myofibroblasts Differentiation and Enhanced Migration by Activation of MMP-9
High mobility group box 1 (HMGB1) is a nuclear protein that involves the binding with DNA and influences chromatin regulation and transcription. HMGB1 is also a cytokine that can activate monocytes and neutrophils involved in inflammation. In this study, we investigated the role of HMGB1 on cellular...
Autores principales: | Lee, Chen-Chen, Wang, Chien-Neng, Lee, Yueh-Lun, Tsai, Yi-Ru, Liu, Jau-Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332862/ https://www.ncbi.nlm.nih.gov/pubmed/25692286 http://dx.doi.org/10.1371/journal.pone.0116393 |
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