Relevance of Simultaneous Mono-Ubiquitinations of Multiple Units of PCNA Homo-Trimers in DNA Damage Tolerance

DNA damage tolerance (DDT) pathways, including translesion synthesis (TLS) and additional unknown mechanisms, enable recovery from replication arrest at DNA lesions. DDT pathways are regulated by post-translational modifications of proliferating cell nuclear antigen (PCNA) at its K164 residue. In pa...

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Detalles Bibliográficos
Autores principales: Kanao, Rie, Masuda, Yuji, Deguchi, Saori, Yumoto-Sugimoto, Mayumi, Hanaoka, Fumio, Masutani, Chikahide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332867/
https://www.ncbi.nlm.nih.gov/pubmed/25692884
http://dx.doi.org/10.1371/journal.pone.0118775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332867/
https://www.ncbi.nlm.nih.gov/pubmed/25692884
http://dx.doi.org/10.1371/journal.pone.0118775

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