Cargando…

Galangin, a novel dietary flavonoid, attenuates metastatic feature via PKC/ERK signaling pathway in TPA-treated liver cancer HepG2 cells

BACKGROUND: Galangin (3,5,7-trihydroxyflavone) is a flavonoid compound found in high concentration in lesser galangal. The objective of this study was to investigate the ability of galangin to inhibit 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced the invasion and metastasis of HepG2 liver cance...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chien, Shang-Tao, Shi, Ming-Der, Lee, Yi-Chieh, Te, Chou-Chia, Shih, Yuan-Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332891/ https://www.ncbi.nlm.nih.gov/pubmed/25698902 http://dx.doi.org/10.1186/s12935-015-0168-2

Ejemplares similares

Galangin Induces Autophagy via Deacetylation of LC3 by SIRT1 in HepG2 Cells
por: Li, Xv, et al.
Publicado: (2016)

Antiproliferative and apoptotic effects of β-elemene on human hepatoma HepG2 cells
por: Dai, Zhi-Jun, et al.
Publicado: (2013)

PKCα mediated induction of miR-101 in human hepatoma HepG2 cells
por: Chiang, Chao-Wei, et al.
Publicado: (2010)

Eurycomanone induce apoptosis in HepG2 cells via up-regulation of p53
por: Zakaria, Yusmazura, et al.
Publicado: (2009)

Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation
por: Yu, Rong, et al.
Publicado: (2014)

Multifunctional selenium nanoparticles with Galangin-induced HepG2 cell apoptosis through p38 and AKT signalling pathway
por: Li, Yinghua, et al.
Publicado: (2018)

Antisense oligonucleotide inhibition of hepatitis C virus genotype 4 replication in HepG2 cells
por: El Awady, Mostafa K, et al.
Publicado: (2006)

Release and uptake of volatile organic compounds by human hepatocellular carcinoma cells (HepG2) in vitro
por: Mochalski, Paweł, et al.
Publicado: (2013)

LATS2 overexpression attenuates the therapeutic resistance of liver cancer HepG2 cells to sorafenib-mediated death via inhibiting the AMPK–Mfn2 signaling pathway
por: Song, Jie, et al.
Publicado: (2019)

MicroRNA-146a promotes proliferation, migration, and invasion of HepG2 via regulating FLAP
por: Wang, Huihui, et al.
Publicado: (2022)

Galangin and Pinocembrin from Propolis Ameliorate Insulin Resistance in HepG2 Cells via Regulating Akt/mTOR Signaling
por: Liu, Yinkang, et al.
Publicado: (2018)

Arsenic trioxide reduces chemo-resistance to 5-fluorouracil and cisplatin in HBx-HepG2 cells via complex mechanisms
por: Yu, Guifang, et al.
Publicado: (2015)

The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma
por: Kong, Yang, et al.
Publicado: (2019)

In Silico Target Identification of Galangin, as an Herbal Flavonoid against Cholangiocarcinoma
por: Balasubramanian, Brinda, et al.
Publicado: (2022)

Epistructured catechins, EGCG and EC facilitate apoptosis induction through targeting de novo lipogenesis pathway in HepG2 cells
por: Khiewkamrop, Phuriwat, et al.
Publicado: (2018)

CpG oligodeoxynucleotides enhance chemosensitivity of 5-fluorouracil in HepG2 human hepatoma cells via downregulation of the antiapoptotic factors survivin and livin
por: Liang, Sheng-ran, et al.
Publicado: (2013)

ESC reverses epithelial mesenchymal transition induced by transforming growth factor-β via inhibition of Smad signal pathway in HepG2 liver cancer cells
por: Liu, Xiao-Ni, et al.
Publicado: (2015)

RNAi silencing of c-Myc inhibits cell migration, invasion, and proliferation in HepG(2) human hepatocellular carcinoma cell line: c-Myc silencing in hepatocellular carcinoma cell
por: Zhao, Yan, et al.
Publicado: (2013)

B7-H4 expression is upregulated by PKCδ activation and contributes to PKCδ-induced cell motility in colorectal cancer
por: Zhou, Bin, et al.
Publicado: (2022)

Apigenin, a dietary flavonoid, inhibits proliferation of human bladder cancer T-24 cells via blocking cell cycle progression and inducing apoptosis
por: Shi, Ming-Der, et al.
Publicado: (2015)

Galangin, a dietary flavonoid, ameliorates hyperglycaemia and lipid abnormalities in rats with streptozotocin-induced hyperglycaemia
por: Aloud, Amal A., et al.
Publicado: (2018)

Galangin, a natural flavonoid reduces mitochondrial oxidative damage in streptozotocin-induced diabetic rats
por: Aloud, Amal A., et al.
Publicado: (2017)

Anti-adipogenic effect of the flavonoids through the activation of AMPK in palmitate (PA)-treated HepG2 cells
por: Rajan, Priyanka, et al.
Publicado: (2021)

Nanoceria Attenuated High Glucose-Induced Oxidative Damage in HepG2 Cells
por: Shokrzadeh, Mohammad, et al.
Publicado: (2016)

The flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor
por: Ciolino, H P, et al.
Publicado: (1999)

Surfactin-Induced Apoptosis Through ROS–ERS–Ca(2+)-ERK Pathways in HepG2 Cells
por: Wang, Chun-ling, et al.
Publicado: (2013)

Flavonoids from Camellia sinensis (L.) O. Kuntze seed ameliorates TNF-α induced insulin resistance in HepG2 cells
por: Chen, Fu-Chih, et al.
Publicado: (2019)

Hepatoprotective effects of flavonoids from common buckwheat hulls in type 2 diabetic rats and HepG2 cells
por: Wang, Hai, et al.
Publicado: (2021)

Lipid Accumulation in HepG2 Cells Is Attenuated by Strawberry Extract through AMPK Activation
por: Forbes-Hernández, Tamara Y., et al.
Publicado: (2017)

Piceatannol attenuates fat accumulation and oxidative stress in steatosis-induced HepG2 cells
por: Yang, Jason Szuhao, et al.
Publicado: (2020)

The Effect of Galangin on the Regulation of Vascular Contractility via the Holoenzyme Reactivation Suppressing ROCK/CPI-17 rather than PKC/CPI-17
por: Yoon, Hyuk-Jun, et al.
Publicado: (2022)

Thrombolytic tPA-induced hemorrhagic transformation of ischemic stroke is mediated by PKCβ phosphorylation of occludin
por: Goncalves, Andreia, et al.
Publicado: (2022)

Flavonoids Enhance Lipofection Efficiency and Ameliorate Cytotoxicity in Colon26 and HepG2 Cells via Oxidative Stress Regulation
por: Hu, Die, et al.
Publicado: (2022)

Iron elevates mesenchymal and metastatic biomarkers in HepG2 cells
por: Mehta, Kosha J., et al.
Publicado: (2020)

Galangin Attenuates Isoproterenol-Induced Inflammation and Fibrosis in the Cardiac Tissue of Albino Wistar Rats
por: Thangaiyan, Radhiga, et al.
Publicado: (2020)

Rifampicin induces clathrin-dependent endocytosis and ubiquitin–proteasome degradation of MRP2 via oxidative stress-activated PKC-ERK/JNK/p38 and PI3K signaling pathways in HepG2 cells
por: Xu, Bao-yan, et al.
Publicado: (2019)

Toxicity Assessment of Octachlorostyrene in Human Liver Carcinoma (HepG2) Cells
por: Ren, Guofa, et al.
Publicado: (2022)

Infliximab Exerts No Direct Hepatotoxic Effect on HepG2 Cells In Vitro
por: de Vries, Hilbert S., et al.
Publicado: (2012)

Natural Thiols, but Not Thioethers, Attenuate Patulin-Induced Endoplasmic Reticulum Stress in HepG2 Cells
por: Kim, Hye Mi, et al.
Publicado: (2021)

Cyclocarya paliurus extract attenuates hepatic lipid deposition in HepG2 cells by the lipophagy pathway
por: Yang, Wanwei, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_13eup7iuak27o6gn34bc03rg32