Galectin-3 mediates bone marrow microenvironment-induced drug resistance in acute leukemia cells via Wnt/β-catenin signaling pathway

BACKGROUND: Acute leukemia is currently the major cause of death in hematological malignancies. Despite the rapid development of new therapies, minimal residual disease (MRD) continues to occur and leads to poor outcomes. The leukemia niche in the bone marrow microenvironment (BMM) is thought to be...

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Detalles Bibliográficos
Autores principales: Hu, Kaimin, Gu, Yanjun, Lou, Lixia, Liu, Lizhen, Hu, Yongxian, Wang, Binsheng, Luo, Yi, Shi, Jimin, Yu, Xiaohong, Huang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332970/
https://www.ncbi.nlm.nih.gov/pubmed/25622682
http://dx.doi.org/10.1186/s13045-014-0099-8

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