Switched-memory B cells remodel B cell receptors within secondary germinal centers

Effective vaccines induce high-affinity memory B cells and durable antibody responses through accelerated mechanisms of natural selection. Secondary changes in antibody repertoires after vaccine boosts suggest progressive B cell receptor (BCR) re-diversification, but underlying mechanisms remain unr...

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Detalles Bibliográficos
Autores principales: McHeyzer-Williams, Louise J., Milpied, Pierre J., Okitsu, Shinji L., McHeyzer-Williams, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333102/
https://www.ncbi.nlm.nih.gov/pubmed/25642821
http://dx.doi.org/10.1038/ni.3095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333102/
https://www.ncbi.nlm.nih.gov/pubmed/25642821
http://dx.doi.org/10.1038/ni.3095

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