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TGF-β signaling alters the pattern of liver tumorigenesis induced by Pten inactivation
Hepatocarcinogenesis results from the accumulation of genetic and epigenetic changes in liver cells. A common mechanism through which these alterations induce liver cancer is by deregulating signaling pathways. A number of signaling pathways, including the PI3K/PTEN/AKT and transforming growth facto...
Autores principales: | Morris, Shelli M., Carter, Kelly T., Baek, Ji Yeon, Koszarek, Amanda, Yeh, Matthew M., Knoblaugh, Sue E., Grady, William M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333137/ https://www.ncbi.nlm.nih.gov/pubmed/25132272 http://dx.doi.org/10.1038/onc.2014.258 |
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