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Antagonistic Antiviral Activity between IFN-Lambda and IFN-Alpha against Lethal Crimean-Congo Hemorrhagic Fever Virus In Vitro

BACKGROUND AND AIMS: Crimean Congo Hemorrhagic fever virus (CCHFV) is the causative agent of Crimean-Congo hemorrhagic fever, a severe disease with a mortality rate of around 30% in humans. Previous studies demonstrate that pre-treatment with type I IFNs have an antiviral effect against CCHFV, while...

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Detalles Bibliográficos
Autores principales:	Bordi, Licia, Lalle, Eleonora, Caglioti, Claudia, Travaglini, Damiano, Lapa, Daniele, Marsella, Patrizia, Quartu, Serena, Kis, Zoltan, Arien, Kevin K., Huemer, Hartwig P., Meschi, Silvia, Ippolito, Giuseppe, Di Caro, Antonino, Capobianchi, Maria R., Castilletti, Concetta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333211/ https://www.ncbi.nlm.nih.gov/pubmed/25693189 http://dx.doi.org/10.1371/journal.pone.0116816

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