Insulin like growth factor binding protein 7 (IGFBP7) expression is linked to poor prognosis but may protect from bone disease in multiple myeloma

BACKGROUND: Insulin like growth factor binding protein 7 (IGFBP7) is a secreted protein binding insulin like growth factor 1 (IGF-1), insulin, vascular endothelial growth factor A (VEGFA), and activin A. It antagonizes bone morphogenetic proteins and is involved in the tumour propagation of solid as...

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Detalles Bibliográficos
Autores principales: Bolomsky, Arnold, Hose, Dirk, Schreder, Martin, Seckinger, Anja, Lipp, Susanne, Klein, Bernard, Heintel, Daniel, Ludwig, Heinz, Zojer, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333268/
https://www.ncbi.nlm.nih.gov/pubmed/25887188
http://dx.doi.org/10.1186/s13045-014-0105-1

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