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CHOPER Filters Enable Rare Mutation Detection in Complex Mutagenesis Populations by Next-Generation Sequencing

Next-generation sequencing (NGS) has revolutionized genetics and enabled the accurate identification of many genetic variants across many genomes. However, detection of biologically important low-frequency variants within genetically heterogeneous populations remains challenging, because they are di...

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Detalles Bibliográficos
Autores principales:	Salehi, Faezeh, Baronio, Roberta, Idrogo-Lam, Ryan, Vu, Huy, Hall, Linda V., Kaiser, Peter, Lathrop, Richard H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333345/ https://www.ncbi.nlm.nih.gov/pubmed/25692681 http://dx.doi.org/10.1371/journal.pone.0116877

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