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Mechanism of RecQ helicase mechanoenzymatic coupling reveals that the DNA interactions of the ADP-bound enzyme control translocation run terminations

The processing of various DNA structures by RecQ helicases is crucial for genome maintenance in both bacteria and eukaryotes. RecQ helicases perform active destabilization of DNA duplexes, based on tight coupling of their ATPase activity to moderately processive translocation along DNA strands. Here...

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Detalles Bibliográficos
Autores principales:	Sarlós, Kata, Gyimesi, Máté, Kele, Zoltán, Kovács, Mihály
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333385/ https://www.ncbi.nlm.nih.gov/pubmed/25539922 http://dx.doi.org/10.1093/nar/gku1333

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