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Regulation of the transcriptional program by DNA methylation during human αβ T-cell development

Thymocyte differentiation is a complex process involving well-defined sequential developmental stages that ultimately result in the generation of mature T-cells. In this study, we analyzed DNA methylation and gene expression profiles at successive human thymus developmental stages. Gain and loss of...

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Detalles Bibliográficos
Autores principales: Rodriguez, Ramon M., Suarez-Alvarez, Beatriz, Mosén-Ansorena, David, García-Peydró, Marina, Fuentes, Patricia, García-León, María J., Gonzalez-Lahera, Aintzane, Macias-Camara, Nuria, Toribio, María L., Aransay, Ana M., Lopez-Larrea, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333391/
https://www.ncbi.nlm.nih.gov/pubmed/25539926
http://dx.doi.org/10.1093/nar/gku1340