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Regulation of the transcriptional program by DNA methylation during human αβ T-cell development
Thymocyte differentiation is a complex process involving well-defined sequential developmental stages that ultimately result in the generation of mature T-cells. In this study, we analyzed DNA methylation and gene expression profiles at successive human thymus developmental stages. Gain and loss of...
Autores principales: | Rodriguez, Ramon M., Suarez-Alvarez, Beatriz, Mosén-Ansorena, David, García-Peydró, Marina, Fuentes, Patricia, García-León, María J., Gonzalez-Lahera, Aintzane, Macias-Camara, Nuria, Toribio, María L., Aransay, Ana M., Lopez-Larrea, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333391/ https://www.ncbi.nlm.nih.gov/pubmed/25539926 http://dx.doi.org/10.1093/nar/gku1340 |
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