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Absolute binding-free energies between standard RNA/DNA nucleobases and amino-acid sidechain analogs in different environments

Despite the great importance of nucleic acid–protein interactions in the cell, our understanding of their physico-chemical basis remains incomplete. In order to address this challenge, we have for the first time determined potentials of mean force and the associated absolute binding free energies be...

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Detalles Bibliográficos
Autores principales: de Ruiter, Anita, Zagrovic, Bojan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333394/
https://www.ncbi.nlm.nih.gov/pubmed/25550435
http://dx.doi.org/10.1093/nar/gku1344