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Absolute binding-free energies between standard RNA/DNA nucleobases and amino-acid sidechain analogs in different environments
Despite the great importance of nucleic acid–protein interactions in the cell, our understanding of their physico-chemical basis remains incomplete. In order to address this challenge, we have for the first time determined potentials of mean force and the associated absolute binding free energies be...
Autores principales: | de Ruiter, Anita, Zagrovic, Bojan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333394/ https://www.ncbi.nlm.nih.gov/pubmed/25550435 http://dx.doi.org/10.1093/nar/gku1344 |
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