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Switching between polymerase and exonuclease sites in DNA polymerase ε

The balance between exonuclease and polymerase activities promotes DNA synthesis over degradation when nucleotides are correctly added to the new strand by replicative B-family polymerases. Misincorporations shift the balance toward the exonuclease site, and the balance tips back in favor of DNA syn...

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Detalles Bibliográficos
Autores principales:	Ganai, Rais A., Bylund, Göran O., Johansson, Erik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333401/ https://www.ncbi.nlm.nih.gov/pubmed/25550436 http://dx.doi.org/10.1093/nar/gku1353

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