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A modular system of DNA enhancer elements mediates tissue-specific activation of transcription by high dietary zinc in C. elegans
Zinc is essential for biological systems, and aberrant zinc metabolism is implicated in a broad range of human diseases. To maintain homeostasis in response to fluctuating levels of dietary zinc, animals regulate gene expression; however, mechanisms that mediate the transcriptional response to fluct...
Autores principales: | Roh, Hyun Cheol, Dimitrov, Ivan, Deshmukh, Krupa, Zhao, Guoyan, Warnhoff, Kurt, Cabrera, Daniel, Tsai, Wendy, Kornfeld, Kerry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333406/ https://www.ncbi.nlm.nih.gov/pubmed/25552416 http://dx.doi.org/10.1093/nar/gku1360 |
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