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Five checkpoints maintaining the fidelity of transcription by RNA polymerases in structural and energetic details

Transcriptional fidelity, which prevents the misincorporation of incorrect nucleoside monophosphates in RNA, is essential for life. Results from molecular dynamics (MD) simulations of eukaryotic RNA polymerase (RNAP) II and bacterial RNAP with experimental data suggest that fidelity may involve as m...

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Detalles Bibliográficos
Autores principales:	Wang, Beibei, Opron, Kristopher, Burton, Zachary F., Cukier, Robert I., Feig, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333413/ https://www.ncbi.nlm.nih.gov/pubmed/25550432 http://dx.doi.org/10.1093/nar/gku1370

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