Cargando…

SUMO ligase PIAS1 functions as a target gene selective androgen receptor coregulator on prostate cancer cell chromatin

Androgen receptor (AR) is a ligand-activated transcription factor that plays a central role in the development and growth of prostate carcinoma. PIAS1 is an AR- and SUMO-interacting protein and a putative transcriptional coregulator overexpressed in prostate cancer. To study the importance of PIAS1...

Descripción completa

Detalles Bibliográficos
Autores principales:	Toropainen, Sari, Malinen, Marjo, Kaikkonen, Sanna, Rytinki, Miia, Jääskeläinen, Tiina, Sahu, Biswajyoti, Jänne, Olli A., Palvimo, Jorma J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333416/ https://www.ncbi.nlm.nih.gov/pubmed/25552417 http://dx.doi.org/10.1093/nar/gku1375

Ejemplares similares

Crosstalk between androgen and pro-inflammatory signaling remodels androgen receptor and NF-κB cistrome to reprogram the prostate cancer cell transcriptome
por: Malinen, Marjo, et al.
Publicado: (2017)

Long-range activation of FKBP51 transcription by the androgen receptor via distal intronic enhancers
por: Makkonen, Harri, et al.
Publicado: (2009)

SUMOylation regulates the protein network and chromatin accessibility at glucocorticoid receptor-binding sites
por: Paakinaho, Ville, et al.
Publicado: (2021)

SUMOylation modulates the transcriptional activity of androgen receptor in a target gene and pathway selective manner
por: Sutinen, Päivi, et al.
Publicado: (2014)

SUMOylation regulates the chromatin occupancy and anti-proliferative gene programs of glucocorticoid receptor
por: Paakinaho, Ville, et al.
Publicado: (2014)

Global analysis of transcription in castration-resistant prostate cancer cells uncovers active enhancers and direct androgen receptor targets
por: Toropainen, Sari, et al.
Publicado: (2016)

Tomosyn Interacts with the SUMO E3 Ligase PIASγ
por: Geerts, Cornelia J., et al.
Publicado: (2014)

Global SUMOylation on active chromatin is an acute heat stress response restricting transcription
por: Niskanen, Einari A., et al.
Publicado: (2015)

Androgen receptor uses relaxed response element stringency for selective chromatin binding and transcriptional regulation in vivo
por: Sahu, Biswajyoti, et al.
Publicado: (2014)

Necdin Promotes Ubiquitin-Dependent Degradation of PIAS1 SUMO E3 Ligase
por: Gur, Ibrahim, et al.
Publicado: (2014)

A novel role for the SUMO E3 ligase PIAS1 in cancer metastasis
por: Dadakhujaev, Shorafidinkhuja, et al.
Publicado: (2014)

Super-resolution study of PIAS SUMO E3-ligases in hippocampal and cortical neurons
por: Conz, Andrea, et al.
Publicado: (2021)

Differential coregulator requirements for function of the hematopoietic transcription factor GATA-1 at endogenous loci
por: Pope, Nathaniel J., et al.
Publicado: (2010)

Cyclical regulation of the insulin-like growth factor binding protein 3 gene in response to 1α,25-dihydroxyvitamin D(3)
por: Malinen, Marjo, et al.
Publicado: (2011)

PIAS1 Is a GATA4 SUMO Ligase That Regulates GATA4-Dependent Intestinal Promoters Independent of SUMO Ligase Activity and GATA4 Sumoylation
por: Belaguli, Narasimhaswamy S., et al.
Publicado: (2012)

Correction: PIAS1 Is a GATA4 SUMO Ligase That Regulates GATA4-Dependent Intestinal Promoters Independent of SUMO Ligase Activity and GATA4 Sumoylation
por: Belaguli, Narasimhaswamy S., et al.
Publicado: (2012)

Identification of the SUMO E3 ligase PIAS1 as a potential survival biomarker in breast cancer
por: Chanda, Ayan, et al.
Publicado: (2017)

Chromatin modification by SUMO-1 stimulates the promoters of translation machinery genes
por: Liu, Hui-wen, et al.
Publicado: (2012)

Ubiquitin E3 ligase FIEL1 regulates fibrotic lung injury through SUMO-E3 ligase PIAS4
por: Lear, Travis, et al.
Publicado: (2016)

A functional LSD1 coregulator screen reveals a novel transcriptional regulatory cascade connecting R-loop homeostasis with epigenetic regulation
por: Pinter, Sabine, et al.
Publicado: (2021)

DPPA2/4 and SUMO E3 ligase PIAS4 opposingly regulate zygotic transcriptional program
por: Yan, Yao-Long, et al.
Publicado: (2019)

Functional characterization of DnSIZ1, a SIZ/PIAS-type SUMO E3 ligase from Dendrobium
por: Liu, Feng, et al.
Publicado: (2015)

Correction: DPPA2/4 and SUMO E3 ligase PIAS4 opposingly regulate zygotic transcriptional program
por: Yan, Yuelong, et al.
Publicado: (2023)

The chromatin scaffold protein SAFB1 localizes SUMO-1 to the promoters of ribosomal protein genes to facilitate transcription initiation and splicing
por: Liu, Hui-wen, et al.
Publicado: (2015)

The SUMO E3-ligase PIAS1 couples reactive oxygen species-dependent JNK activation to oxidative cell death
por: Leitao, Beatriz B., et al.
Publicado: (2011)

A SUMO-regulated activation function controls synergy of c-Myb through a repressor–activator switch leading to differential p300 recruitment
por: Molværsmyr, Ann-Kristin, et al.
Publicado: (2010)

Transcriptional repressor NIR interacts with the p53-inhibiting ubiquitin ligase MDM2
por: Heyne, Kristina, et al.
Publicado: (2014)

Trophic factor BDNF inhibits GABAergic signaling by facilitating dendritic enrichment of SUMO E3 ligase PIAS3 and altering gephyrin scaffold
por: Thirouin, Zahra S., et al.
Publicado: (2022)

Analysis of SUMO1-conjugation at synapses
por: Daniel, James A, et al.
Publicado: (2017)

Zimp7 and Zimp10, two novel PIAS-like proteins, function as androgen receptor coregulators
por: Beliakoff, Jason, et al.
Publicado: (2006)

SUMO-2 and PIAS1 Modulate Insoluble Mutant Huntingtin Protein Accumulation
por: O’Rourke, Jacqueline Gire, et al.
Publicado: (2013)

Endothelial cell differentiation is encompassed by changes in long range interactions between inactive chromatin regions
por: Niskanen, Henri, et al.
Publicado: (2018)

The E3 SUMO ligase PIASγ is a novel interaction partner regulating the activity of diabetes associated hepatocyte nuclear factor-1α
por: Kaci, Alba, et al.
Publicado: (2018)

Duck PIAS2 Promotes H5N1 Avian Influenza Virus Replication Through Its SUMO E3 Ligase Activity
por: Zu, Shaopo, et al.
Publicado: (2020)

Characterization of a functional endothelial super-enhancer that regulates ADAMTS18 and angiogenesis
por: Mushimiyimana, Isidore, et al.
Publicado: (2021)

Lack of androgen receptor SUMOylation results in male infertility due to epididymal dysfunction
por: Zhang, Fu-Ping, et al.
Publicado: (2019)

SUMOylation of AMPKα1 by PIAS4 specifically regulates mTORC1 signalling
por: Yan, Yan, et al.
Publicado: (2015)

HSCARG, a novel regulator of H2A ubiquitination by downregulating PRC1 ubiquitin E3 ligase activity, is essential for cell proliferation
por: Hu, Bin, et al.
Publicado: (2014)

The E3-ligases SCF(Ppa) and APC/C(Cdh1) co-operate to regulate CENP-A(CID) expression across the cell cycle
por: Moreno-Moreno, Olga, et al.
Publicado: (2019)

Response: Commentary: Analysis of SUMO1-conjugation at synapses
por: Daniel, James A., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ghpktpn6epts12b8nualcntukp