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Transcriptional regulator-mediated activation of adaptation genes triggers CRISPR de novo spacer acquisition

Acquisition of de novo spacer sequences confers CRISPR-Cas with a memory to defend against invading genetic elements. However, the mechanism of regulation of CRISPR spacer acquisition remains unknown. Here we examine the transcriptional regulation of the conserved spacer acquisition genes in Type I-...

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Detalles Bibliográficos
Autores principales:	Liu, Tao, Li, Yingjun, Wang, Xiaodi, Ye, Qing, Li, Huan, Liang, Yunxiang, She, Qunxin, Peng, Nan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333418/ https://www.ncbi.nlm.nih.gov/pubmed/25567986 http://dx.doi.org/10.1093/nar/gku1383

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