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Early Growth Response 3 regulates genes of inflammation and directly activates IL6 and IL8 expression in prostate cancer

BACKGROUND: Transcription factor EGR3 (Early Growth Response 3) is a little-studied member of the EGR family that is highly expressed in human prostate tumours compared with normal tissue. Its function in prostate cancer, however, is unknown. METHODS: Stable shRNA silencing was achieved in naturally...

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Detalles Bibliográficos
Autores principales:	Baron, V T, Pio, R, Jia, Z, Mercola, D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333488/ https://www.ncbi.nlm.nih.gov/pubmed/25633035 http://dx.doi.org/10.1038/bjc.2014.622

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