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Concerted, Rapid, Quantitative, and Site-Specific Dual Labeling of Proteins

[Image: see text] Rapid, one-pot, concerted, site-specific labeling of proteins at genetically encoded unnatural amino acids with distinct small molecules at physiological pH, temperature, and pressure is an important challenge. Current approaches require sequential labeling, low pH, and typically d...

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Detalles Bibliográficos
Autores principales: Sachdeva, Amit, Wang, Kaihang, Elliott, Thomas, Chin, Jason W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333588/
https://www.ncbi.nlm.nih.gov/pubmed/24857040
http://dx.doi.org/10.1021/ja4129789