Complete Genome Sequence of the Human Herpesvirus 6A Strain AJ from Africa Resembles Strain GS from North America

The genome sequence of human herpesvirus 6A (HHV-6A) strain AJ was determined in a comparison of target enrichment and long-range PCR using next-generation sequencing methodologies. The analyses show 85 predicted open reading frames (ORFs), conservation with sequenced HHV-6A reference strain U1102,...

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Autores principales: Tweedy, J., Spyrou, M. A., Donaldson, C. D., Depledge, D., Breuer, J., Gompels, U. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Viruses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333650/
https://www.ncbi.nlm.nih.gov/pubmed/25676750
http://dx.doi.org/10.1128/genomeA.01498-14
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author Tweedy, J.
Spyrou, M. A.
Donaldson, C. D.
Depledge, D.
Breuer, J.
Gompels, U. A.
author_facet Tweedy, J.
Spyrou, M. A.
Donaldson, C. D.
Depledge, D.
Breuer, J.
Gompels, U. A.
author_sort Tweedy, J.
collection PubMed
description The genome sequence of human herpesvirus 6A (HHV-6A) strain AJ was determined in a comparison of target enrichment and long-range PCR using next-generation sequencing methodologies. The analyses show 85 predicted open reading frames (ORFs), conservation with sequenced HHV-6A reference strain U1102, and closest identity to the recently determined GS strain, despite different geographic origins (United States and Gambia).
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spelling pubmed-43336502015-02-20 Complete Genome Sequence of the Human Herpesvirus 6A Strain AJ from Africa Resembles Strain GS from North America Tweedy, J. Spyrou, M. A. Donaldson, C. D. Depledge, D. Breuer, J. Gompels, U. A. Genome Announc Viruses The genome sequence of human herpesvirus 6A (HHV-6A) strain AJ was determined in a comparison of target enrichment and long-range PCR using next-generation sequencing methodologies. The analyses show 85 predicted open reading frames (ORFs), conservation with sequenced HHV-6A reference strain U1102, and closest identity to the recently determined GS strain, despite different geographic origins (United States and Gambia). American Society for Microbiology 2015-02-12 /pmc/articles/PMC4333650/ /pubmed/25676750 http://dx.doi.org/10.1128/genomeA.01498-14 Text en Copyright © 2015 Tweedy et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Viruses
Tweedy, J.
Spyrou, M. A.
Donaldson, C. D.
Depledge, D.
Breuer, J.
Gompels, U. A.
Complete Genome Sequence of the Human Herpesvirus 6A Strain AJ from Africa Resembles Strain GS from North America
title Complete Genome Sequence of the Human Herpesvirus 6A Strain AJ from Africa Resembles Strain GS from North America
title_full Complete Genome Sequence of the Human Herpesvirus 6A Strain AJ from Africa Resembles Strain GS from North America
title_fullStr Complete Genome Sequence of the Human Herpesvirus 6A Strain AJ from Africa Resembles Strain GS from North America
title_full_unstemmed Complete Genome Sequence of the Human Herpesvirus 6A Strain AJ from Africa Resembles Strain GS from North America
title_short Complete Genome Sequence of the Human Herpesvirus 6A Strain AJ from Africa Resembles Strain GS from North America
title_sort complete genome sequence of the human herpesvirus 6a strain aj from africa resembles strain gs from north america
topic Viruses
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333650/
https://www.ncbi.nlm.nih.gov/pubmed/25676750
http://dx.doi.org/10.1128/genomeA.01498-14
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