SLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with Telomeres

SLX4 interacts with several endonucleases to resolve structural barriers in DNA metabolism. SLX4 also interacts with telomeric protein TRF2 in human cells. The molecular mechanism of these interactions at telomeres remains unknown. Here, we report the crystal structure of the TRF2-binding motif of S...

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Detalles Bibliográficos
Autores principales: Wan, Bingbing, Yin, Jinhu, Horvath, Kent, Sarkar, Jaya, Chen, Yong, Wu, Jian, Wan, Ke, Lu, Jian, Gu, Peili, Yu, Eun Young, Lue, Neal F., Chang, Sandy, Liu, Yie, Lei, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334113/
https://www.ncbi.nlm.nih.gov/pubmed/24012755
http://dx.doi.org/10.1016/j.celrep.2013.08.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334113/
https://www.ncbi.nlm.nih.gov/pubmed/24012755
http://dx.doi.org/10.1016/j.celrep.2013.08.017

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