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P-TEFb, the Super Elongation Complex and Mediator Regulate a Subset of Non-paused Genes during Early Drosophila Embryo Development

Positive Transcription Elongation Factor b (P-TEFb) is a kinase consisting of Cdk9 and Cyclin T that releases RNA Polymerase II (Pol II) into active elongation. It can assemble into a larger Super Elongation Complex (SEC) consisting of additional elongation factors. Here, we use a miRNA-based approa...

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Detalles Bibliográficos
Autores principales:	Dahlberg, Olle, Shilkova, Olga, Tang, Min, Holmqvist, Per-Henrik, Mannervik, Mattias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334199/ https://www.ncbi.nlm.nih.gov/pubmed/25679530 http://dx.doi.org/10.1371/journal.pgen.1004971

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