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The Importance of Ensemble Averaging in Enzyme Kinetics
[Image: see text] The active site of an enzyme is surrounded by a fluctuating environment of protein and solvent conformational states, and a realistic calculation of chemical reaction rates and kinetic isotope effects of enzyme-catalyzed reactions must take account of this environmental diversity....
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334256/ https://www.ncbi.nlm.nih.gov/pubmed/25539028 http://dx.doi.org/10.1021/ar500319e |