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Heat Stress-Induced Disruption of Endothelial Barrier Function Is via PAR1 Signaling and Suppressed by Xuebijing Injection

Increased vascular permeability leading to acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) is central to the pathogenesis of heatstroke. Protease-activated receptor 1 (PAR1), the receptor for thrombin, plays a key role in disruption of endothelial barrier function in response...

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Detalles Bibliográficos
Autores principales:	Xu, Qiulin, Liu, Jingxian, Wang, Zhenglian, Guo, Xiaohua, Zhou, Gengbiao, Liu, Yanan, Huang, Qiaobing, Su, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334482/ https://www.ncbi.nlm.nih.gov/pubmed/25693178 http://dx.doi.org/10.1371/journal.pone.0118057

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