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CD8 T Cell Response Maturation Defined by Anentropic Specificity and Repertoire Depth Correlates with SIVΔnef-induced Protection

The live attenuated simian immunodeficiency virus (LASIV) vaccine SIVΔnef is one of the most effective vaccines in inducing protection against wild-type lentiviral challenge, yet little is known about the mechanisms underlying its remarkable protective efficacy. Here, we exploit deep sequencing tech...

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Detalles Bibliográficos
Autores principales:	Adnan, Sama, Colantonio, Arnaud D., Yu, Yi, Gillis, Jacqueline, Wong, Fay E., Becker, Ericka A., Piatak, Michael, Reeves, R. Keith, Lifson, Jeffrey D., O’Connor, Shelby L., Johnson, R. Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334552/ https://www.ncbi.nlm.nih.gov/pubmed/25688559 http://dx.doi.org/10.1371/journal.ppat.1004633

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