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The effect of nilotinib plus arsenic trioxide on the proliferation and differentiation of primary leukemic cells from patients with chronic myoloid leukemia in blast crisis

AIM: To determine the effects of arsenic trioxide (ATO) and nilotinib (AMN107, Tasigna) alone or in combination on the proliferation and differentiation of primary leukemic cells from patients with chronic myeloid leukemia in the blast crisis phase (CML-BC). METHODS: Cells were isolated from the bon...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Lv, Fei-fei, Du, Yan, Li, Nannan, Chen, YaLing, Chen, LiHong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334604/
https://www.ncbi.nlm.nih.gov/pubmed/25698901
http://dx.doi.org/10.1186/s12935-015-0158-4