The Interplay between Cyclic AMP, MAPK, and NF-κB Pathways in Response to Proinflammatory Signals in Microglia

Cyclic AMP is an important intracellular regulator of microglial cell homeostasis and its negative perturbation through proinflammatory signaling results in microglial cell activation. Though cytokines, TNF-α and IL-1β, decrease intracellular cyclic AMP, the mechanism by which this occurs is poorly...

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Detalles Bibliográficos
Autores principales: Ghosh, Mousumi, Aguirre, Vladimir, Wai, Khine, Felfly, Hady, Dietrich, W. Dalton, Pearse, Damien D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334621/
https://www.ncbi.nlm.nih.gov/pubmed/25722974
http://dx.doi.org/10.1155/2015/308461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334621/
https://www.ncbi.nlm.nih.gov/pubmed/25722974
http://dx.doi.org/10.1155/2015/308461

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